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Meta-Kinesis
May 2020OnlineTEXT Overstep Maria Almpani, Yota Dimitriou CURATED Strong Maria Almpani, Yota Dimitriou TRANSLATION Alongside Yota Dimitriou PARTICIPANTS Historiographer Bitsikas, Manolis Charos, Vana Fertaki, Michalis Kallimopoulos, Martyr Kazazis, Kostas Lavdas, Dimitra Lazaridou, Michalis Manousakis, Aphasia Marouli, Irene Matsouki, Kyriaki Mavrogeorgi, Katerina Mertzani, Tassos Missouras, Kyriakos Mortarakos, Ilias Papailiakis, Konstantinos Patsios, Vangelis Pliarides, Spiridoula Politi, Mantalina Psoma, Panagiotis Siagris, Stamatis Theocharis, Andreas Voussouras
Dimitra Lazaridou,
Blue(s) warning. (Y. Klein's option),
Color motion picture on Archival cotton carve,
53x67 cm,
Edition 1/9
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Biography
Born in Athens. Lives and works in Berlin and Athens.
Co-founder of the Athens art and video platform intothepill (2006-2010) and the Berlin
based art group mokotomoro in 2012.
Education:
1989-1993, BA, Graphic design, University of West Attica, Department of Graphic Arts and Creative Studies, Athens.
1994-1999, MA Fine Arts, Athens School of Fine Arts.
1996-1998, Alkminis acting school, Athens.
1998, Sculpture and Multimedia, School of Fine Arts, The Hague/ Netherland.
Exhibitions:
2024, Art Athina, Art fair with Athanasiadou gallery, Zappion Mansion, Athens.
2024, Cinefix, Feminist classics: Video Art from the EMST collection, National Museum of Contemporary Art, Athens.
2024, AutoKino Extented, Autoteile project space, Berlin.
2024, Group show, Athannasiadou gallery, Thessaloniki.
2024, As long as I remember, as fast as I remember, as strong as I remember,
curated by Ferdinand Waas, K4 gallery, Oslo.
2023, Nova Bienal Rio of art and technology, Museum of Tomorrow, Rio de Janeiro.
2023, J.I. , screening / talk, HilbertRaum project space, Berlin.
2023, Free associations, Poly and Christos Kollialis collection, curated by Machi
Pesmatzoglou, Archaeological Museum of Thessaloniki.
2023, All together I, Zina Athanasiadou Gallery
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Abstract
Antibiotic tolerance and antibiotic resistance are the two major obstacles to the efficient and reliable treatment of bacterial infections. Identifying antibiotic adjuvants that sensitize resistant and tolerant bacteria to antibiotic killing may lead to the development of superior treatments with improved outcomes. Vancomycin, a lipid II inhibitor, is a frontline antibiotic for treating methicillin-resistant Staphylococcus aureus and other Gram-positive bacterial infections. However, vancomycin use has led to the increasing prevalence of bacterial strains with reduced susceptibility to vancomycin. Here, we show that unsaturated fatty acids act as potent vancomycin adjuvants to rapidly kill a range of Gram-positive bacteria, including vancomycin-tolerant and resistant populations. The synergistic bactericidal activity relies on the accumulation of membrane-bound cell wall intermediates that generate large fluid patches in the membrane leading to protein delocalization, aberrant septal formation, and loss of membrane integrity. Our findings provide a natural therapeutic option that enhances vancomycin activity against difficult-to-treat pathogens, and the underlying mechanism may be further exploited to develop antimicrobials that target recalcitrant infection.
Res